Endothelial dysfunction is associated with ongoing activation of the type I interferon system and platelets in patients with systemic lupus erythematosus
نویسندگان
چکیده
platelets in patients with systemic lupus erythematosus Helena Tydén, Christian Lood, Birgitta Gullstrand, Christoffer T. Nielsen, Niels H.H. Heegaard, Robin Kahn, Andreas Jönsen and Anders A. Bengtsson. 1.Department of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden 2.Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark 3.Copenhagen Lupus and Vasculitis Clinic, Centre for Rheumatology & Spine Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark 4.Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense Denmark 5. Department of Paediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden
منابع مشابه
Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus
Objectives Endothelial dysfunction may be connected to cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Type I interferons (IFNs) are central in SLE pathogenesis and are suggested to induce both endothelial dysfunction and platelet activation. In this study, we investigated the interplay between endothelial dysfunction, platelets and type I IFN in SLE. Methods We enrolled 1...
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تاریخ انتشار 2017